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Febrile neutrophilic dermatosis : ウィキペディア英語版
Febrile neutrophilic dermatosis

Sweet's syndrome (SS), or acute febrile neutrophilic dermatosis is a skin disease characterized by the sudden onset of fever, an elevated white blood cell count, and tender, red, well-demarcated papules and plaques that show dense infiltrates by neutrophil granulocytes on histologic examination.
The syndrome was first described in 1964 by Dr. Robert Douglas Sweet. It was also known as Gomm-Button disease in honour of the first two patients Dr. Sweet diagnosed with the condition.
==Definition==
Sweet, working in Plymouth in 1964, described a disease with four features: fever; leukocytosis; acute, tender, red plaques; and a papillary dermal infiltrate of neutrophils. This led to the name acute febrile neutrophilic dermatosis. Larger series of patients showed that fever and neutrophilia are not consistently present. The diagnosis is based on the two constant features, a typical eruption and the characteristic histologic features; thus the eponym "Sweet's syndrome" is used.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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